Places of Interest Near Matlacha Isles, Florida
| Airport - Transportation | Location | Distance & Direction |
| Charlotte County Airport (PGD) | Punta Gorda | 20.2 miles NNE |
| Southwest Florida International Airport (RSW) | Fort Myers | 20.3 miles ESE |
| Churchs - Places of Worship - Wedding Chapels | Location | Distance & Direction |
| Burroughs Home | Fort Myers | 12.1 miles E |
| Hospitals & Medical Care Facilities | Location | Distance & Direction |
| Cape Coral Hospital | Cape Coral | 7.6 miles E |
| Lee Memorial Health System | Fort Myers | 11.9 miles E |
| Riverwalk Surgery Center | fort myers | 12 miles ESE |
| Sfi Ambulatory Surgery Inc | fort myers | 12.5 miles E |
| University Eye Surgery Center | fort myers | 12.6 miles ESE |
| Summerlin Bend Surgery Center | fort myers | 12.8 miles ESE |
| Surgi Care Center | fort myers | 12.8 miles E |
| Southwest Regional Medical Center | fort myers | 13 miles E |
| Healthpark Medical Center | fort myers | 13.3 miles SE |
| Gulf Coast Hospital | Fort Myers | 14.7 miles ESE |
| Charlotte Regional Medical Center | Punta Gorda | 21.2 miles N |
| Fawcett Memorial Hospital | Port Charlotte | 24.4 miles N |
| Bon Secours- St Joseph Health | Port Charlotte | 24.5 miles N |
| Museums | Location | Distance & Direction |
| Edison & Ford Winter Estates | Fort Myers | 11.4 miles E |
| Railroad Museum South Florida | fort myers | 11.6 miles ESE |
| Calusa Nature Ctr and Planetarum | fort myers | 15.7 miles E |
| Florida Adventure Museum | Punta Gorda | 20.7 miles N |
| Resorts - Spas- Camping - RV Parks | Location | Distance & Direction |
| Discover Resort's Florida | sanibel | 13.2 miles S |
| Fisherman's Village Resort Club | Punta Gorda | 20.2 miles N |
| Shopping | Location | Distance & Direction |
| Edison Mall | Fort Myers | 12.2 miles E |
| Stadiums - Arenas - Athletic Fields | Location | Distance & Direction |
| Hammond Stadium - Fort Myers Miracle | Fort Myers | 14.9 miles ESE |
| Lee County Sports Complex | fort myers | 15.4 miles ESE |
